The main squeeze for the guys was two firebrands. Cat-Girl lost her powers due to radiation while Nova gained powers by radiation! However, Nova's new lease on life (caused by an inner Earth sun going nova itself) caused her to lose her humanity. She later lost them.... only to regain them later (with a different comic book publisher).
Two malevolent lasses from outer space caused the dudes some difficulties, Kree-Nal an alien siren that changed men to beasts and Vamfire, an energy being created by the same nova E-Man came from! Both dropped their harsher edges. Vamfire found love, a mutated human named Eco-Man, while Kree-Nal swam alone.
Eventually, the "E"-nimals' girls joined forces to show them that the fairer sex packs a punch. While E-Man eventually succumbed to his overwhelming feelings for Nova (plus, Vamfire was kinda his "sister" so it would be gross if they paired up, and Rosie just never had the E-chemistry going for her), Jaguar and his alias Ralph Hardy stayed the Lady's Man that never settled down with any of the gals. Both chick magnets!